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Aprima contains the active ingredient apomorphine hydrochloride and works in a completely different manner to other forms of treatment of erectile dysfunction ( E.D. ). Apomorphine hydrochloride is known as a dopamine agonist and works by enhancing the nerve signals that produce an erection. During sexual stimulation, nerve signals are sent from the brain to the penis. This causes the blood vessels in the penis to widen and relax producing an erection. Apomorphine mimicks the action of dopamine, a naturally occuring chemical neurotransmitter. Neurotransmitters are responsible for sending signals along nerves. Dopamine acts on dopamine receptors in an area of the brain called the hypothalamus causing nerve signals that produce an erection to be sent to the penis. It is the dopamine enhancing effect of apomorphine hydrochloride that makes Aprima a truly unique product. As a result of the enhanced effect of naturally occuring dopamine, nerve signals to the penis are enhanced ultimately causing it to become erect during sexual stimulation. Aprima has certain advantages over traditional treatments of E.D. such as Kamagra. Aprima dissolves under the tongue in under 10 minutes largely bypassing the normal digestive system. Its absorbsion, therefore, is not affected by food or alcohol. This results in much quicker onset of effects, typically in around 15-20 minutes compared to 45-60 minutes for sildenafil citrate ( Kamagra ) tablets making sexual activity more spontaneous and natural. Also,the sublingual absorbsion of the pill is ideal for people who have difficulty swallowing tablets. Side effects tend to be very mild for the majority of users while at the same time remaining a potent and effective treatment of E.D. Cinical trials have demonstrated an improvement in erections in at least 88% of participants.

Apcalis Tablets and Oral Jellies work in much the same way as Kamagra, except the effects last much longer (typically 24-36 hours) As with Kamagra, Apcalis is also a PDE-5 inhibitor. Similar precautions should also be taken before taking Apcalis Tablets and Oral Jelly (see precautions before taking Apcalis). Apcalis should not be taken more than once a day. Daily use of Apcalis is not recommended.


Warnings/Precautions
Do not take Kamagra if you are taking any nitrate-based drug, including nitroglycerin patches (Nitro-Dur, Transderm-Nitro), nitroglycerin ointment (Nitro-Bid, Nitrol), nitroglycerin pills (Nitro-Bid, Nitrostat), and isosorbide pills (Dilatrate-SR, Isordil, Sorbitrate). Combining Kamagra with these drugs can cause a severe drop in blood pressure.

If you have heart problems severe enough to make sexual activity a danger, you should avoid using Kamagra. Use it cautiously if you've had a heart attack, stroke, or life-threatening heart irregularities within the past 6 months. Be equally cautious if you have severe high or low blood pressure, heart failure, or unstable angina.

If you take Kamagra and develop cardiac symptoms (for example, dizziness, nausea, and chest pain) during sexual activity, do not continue. Alert your doctor to the problem as soon as possible.

If you have a condition that might result in long-lasting erections, such as sickle cell anemia, multiple myeloma (a disease of the bone marrow), or leukemia, use Kamagra with caution. Also use cautiously if you have a genital problem or deformity such as Peyronie's disease. If an erection lasts more than 4 hours, seek treatment immediately. Permanent damage and impotence could result.

If you have a bleeding disorder, a stomach ulcer, or the inherited eye condition known as retinitis pigmentosa, use Kamagra with caution. Its safety under these circumstances has not yet been studied.

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